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Topamax is an anticonvulsant used to treat epilepsy and migraines. It increases activity of a substance in the brain called gamma-aminobutyric acid. topiramate online A change in dose will have a higher risk of recurrence of seizures, even if seizures have ceased for a long time. A change in dose will have a higher risk of recurrence of seizures, even if seizures have ceased for a long time.